Apalachicola offers plenty of vacation rental options, from beach houses to condos to hotels, plus several charming bed-and-breakfast inns. Among the choices are the award-winning Coombs House bed and breakfast and the 30-suite Water Street Hotel and Marina. Both are pet-friendly and within walking distance of shops and restaurants.

To see photos, amenities, and other details on Apalachicola vacation rentals, choose from our list to browse all the options—or use the custom search feature to quickly find exactly what is best for you. Don’t forget to check our beach deals for special rental rates.